Peyronie’s disease is a disorder that causes areas of hardened scar tissue called plaques to form on the penis, just under the surface of the skin. These plaques make the penis less flexible. As a result, men with Peyronie’s disease have a noticeable curve in their penis. The penis may shorten as well.

Hypoactive sexual desire disorder (HSDD) is a troublesome condition in which women lose interest in sex. The Society for Women’s Health Research estimates that one in ten women have HSDD, making it one of the most common female sexual health complaints.

Men with anejaculation cannot ejaculate semen. Their bodies can still produce sperm, and they might still feel pleasure with orgasm, but no semen comes forth through the penis when they climax.

Pharmacologic treatment of premature ejaculation represents a new approach to the treatment of PE and a radical departure from the psychosexual model of treatment. There have been many papers discussing this topic. I chose to write a clinical paper, in the form of Questions and Answers, which is an innovative way of writing an article (with several citations) to help clinicians in the management of premature ejaculation.

Michael A. Perelman, Ph.D.

N. Y. Weill Cornell Medical Center

New York, N.Y. USA

February 2009