Introduction

Gender incongruence (GI) occurs when a person’s gender identity doesn’t match the gender they were assigned at birth, sometimes leading to significant mental health challenges like anxiety, depression, and suicidal thoughts. These issues often stem from both the internal conflict of gender misalignment and external pressures such as stigma and hiding one’s true identity.

Introduction

Urinary tract infections (UTIs) are very common, especially among women, with up to 60% experiencing one at some point. About 25% of these women will have recurrent UTIs (rUTIs), which negatively affect their quality of life, social relationships, sexual relationships, and self-esteem, causing issues like irritability and tiredness. Women with rUTIs often experience sexual problems, such as pain during intercourse, anxiety or fear about getting another UTI, and lubrication issues.

Introduction

Erectile dysfunction (ED) is the ongoing inability to get or keep an erection firm enough for sex. It affects up to 47% of men and becomes more common with age, increasing from 5% in men in their 40s to 15% in their 70s. Factors like high blood pressure, diabetes, smoking, alcohol use, obesity, and abnormal cholesterol levels contribute to ED and also to heart disease. Both conditions involve problems with blood vessels, making ED a potential early warning sign for heart disease.

Introduction

As people live longer, the global population of older adults is increasing rapidly. In 2019, there were 703 million individuals aged 65 and older, a number expected to double by 2050. Promoting health and well-being for this age group is a public health priority.

Introduction

Hypoactive sexual desire disorder (HSDD) is a medical condition that affects many women, causing low libido and distress. It has been established that low levels of testosterone can cause low libido in men, and testosterone therapy (TTh) can be an effective treatment option. Testosterone therapy has also shown promise in treating HSDD in women, especially postmenopausal women, improving sexual function and satisfaction.

Introduction

In recent years, there has been a rise in referrals for gender incongruence assessment globally, including in Denmark. Estimating the transgender and gender-diverse population remains challenging, with estimates ranging from 0.02% to 4.5% of the adult population. Individuals experiencing gender incongruence often face psychological vulnerabilities, including depression, anxiety, and increased risk of suicide attempts, alongside reduced quality of life and higher rates of substance abuse.