In this ISSM Podcast episode, Tanginika S. Cuascud continues her conversation with Rachel Rubin, focusing on hormone therapy and its impact on women’s health. They examine the long-lasting effects of the Women’s Health Initiative and how fear-driven messaging has influenced both patients and clinicians for decades. Dr. Rubin discusses recent changes in regulatory guidance and the challenges of reversing deeply ingrained misconceptions in medical practice. The discussion also addresses the role of testosterone in women, common barriers to prescribing it, and the broader need for education, advocacy, and accessible care to better support women navigating midlife health changes.