Mario Maggi, Sexual Medicine & Andrology, University of Florence, Florence, Italy. April 2008 Prostate cancer cells express androgen receptors that bind testosterone and, with an higher affinity, its 5a-reduced product, DHT, and that transmit proliferative signals (Crescioli et al., Endocrinology, 144:3046, 2003). The pioneering work of Huggins (Cancer Res 1:293-7, 1941) gave rise to the […]