Psychedelic drugs are recreational substances that cause an elevated state of mind, altering perception, enhancing mood, and changing consciousness by changing the way serotonin acts in the brain. Essentially, drugs like magic mushrooms, LSD, and MDMA (molly) can cause hallucinations; commonly known as “tripping” to those who use these substances.

Some other naturally occurring psychedelics include ayahuasca, ketamine, and ibogaine. Overuse of psychedelics can result in memory loss, anxiety, mood swings, paranoia, severe rises in blood pressure, and nausea. It should be mentioned that these drugs are controlled substances for a reason.

Because of the increase in psychedelic use since at least the 1970s, there has also been an increase in research into the effects psychedelics have on sexual functioning and risky sexual behavior.

Positive Effects on Sexual Functioning

Some studies have shown that psychedelics can enhance sexual experiences. Because of their reaction with serotonin and their hallucinogenic properties, psychedelics may increase satisfaction and intensity with orgasm. They may also make the sexual experience feel longer and more intense.

Based on a study comparing recreational magic mushroom users to patients using depression medications, which both limit serotonin uptake, it appears that psychedelics may enhance communication between partners. This same study suggested that the magic mushroom users were more open to trying new things with sex and may have viewed sex more as a spiritual experience.

Negative Effects on Sexual Functioning

Excessive use of psychedelic substances is more likely to hinder sexual function than help. Substance abuse disorder is a serious mental health condition that can lead to worsened quality of life and, in extreme cases, death. With the substance abuse of psychedelics, researchers have found that sexual function is diminished.

Men, for example, may have higher chances of issues with erectile dysfunction, anorgasmia (lack of or inconsistent orgasms), and premature ejaculation. Women who use psychedelics may experience a lack of lubrication, which can often lead to irritation and dyspareunia (pain with penetrative sex), as well as higher chances of experiencing anorgasmia. Both men and women are likely to experience bouts of low libido (low sex drive).

Use of any recreational or controlled substance can lead to risky sexual behavior, such as having sex without contraceptive measures or engaging with multiple sexual partners. These behaviors may result in sexually transmitted infections (STIs) or unwanted pregnancy. As with any other instance of inhibited thinking, those who have taken psychedelics may also be unable to give full consent to sexual activity.

Key Takeaways

• Psychedelics are recreational substances that often result in heightened mood and an altered perception of reality, or hallucinations.
• Use of psychedelics may increase the positive sensations of sex, resulting in more intense experiences and orgasms.
• Use of psychedelics in excess can result in serious consequences.
  • Long-term psychedelic use may result in worsened sexual function, leading to pain with sex, low libido, and erectile or ejaculatory problems.
  • Risky sexual behavior can result in STIs, unwanted pregnancy, or unwanted sexual situations.
• Substance abuse disorder is a serious illness that may require intervention from a mental health professional.

Resources

• Barba, T., Kettner, H., Radu, C., Peill, J. M., Roseman, L., Nutt, D. J., Erritzoe, D., Carhart-Harris, R., & Giribaldi, B. (2024). Psychedelics and sexual functioning: A mixed-methods study. Scientific Reports, 14(1). https://doi.org/10.1038/s41598-023-49817-4
• Mutha, A. S., Mulay, A. M., Reddy, D. N., Rao, T. S., & Langade, D. (2025). Exploring pleasure and risks: The interplay between recreational substances and sexual health. Journal of Psychosexual Health, 7(1), 18–28. https://doi.org/10.1177/26318318241287173
• Soltaninejad, M., Naderi, Y., Rouhi, L., & Banazadeh, M. (2024). Substance abuse and sexual functioning: An overview of mechanisms. Addiction and Health, 16(4), 286–296. https://doi.org/10.34172/ahj.1515