Peyronie’s disease is marked by penile curvature and plaques – areas of hardened scar tissue on the penis. The plaques form on the tunica albuginea, an elastic sheath that surrounds spongy erectile tissue. Plaques cause the tunica albuginea to lose some flexibility, which is why the penis bends when erect. The curvature can also cause pain.
In a plaque incision and graft procedure (sometimes called a Horton-Devine procedure), a surgeon cuts into the plaque, straightens the penis, and fills the cut area with stretchable material called a graft. For men with Peyronie’s disease, a graft can bring back the flexibility needed for erection.