Researchers have discovered a combination of compounds that may help in the treatment of Peyronie’s disease in its active phase, according to a recent study in European Urology. After testing 21 substances in an phenotypic screening assay and working with rat models, they determined that the combination of vardenafil [a phosphodiesterase type 5 (PDE5) inhibitor] […]
Erectile Dysfunction a Concern for Childhood Cancer Survivors
Erectile dysfunction (ED) affects about three in ten male childhood cancer survivors, scientists report, adding that ED “may be a modifiable condition” for this population. Their study, discussed in a recent research letter in JAMA Oncology, involved 1,021 male childhood cancer survivors between the ages of 19 and 62 (median age 31 years). At least […]
Peyronie’s Disease: Should Sildenafil be Added to CCH Therapy?
Sildenafil 25 mg ODT + Collagenase Clostridium histolyticum vs Collagenase Clostridium histolyticum Alone for the Management of Peyronie’s Disease: A Matched-Pair Comparison Analysis Andrea Cocci MD, PhD; Gianmartin Cito MD; Daniele Urzì MD; Andrea Minervini MD; Fabrizio Di Maida MD; Francesco Sessa MD; Andrea Mari MD; Riccardo Campi MD; Marco Falcone MD; Marco Capece MD; […]
Mindfulness Therapy for ED Feasible, Warrants Further Research
Mindfulness-based group therapy is a feasible method for treating men with situational erectile dysfunction (ED), according to a recent pilot study in the Journal of Sexual Medicine. The therapy, which involves “non-judgmental present-moment awareness” has been beneficial for women with sexual dysfunction in the past, as it reduces anxiety and sexual distress. However, little was […]
Sildenafil Overdose Leads to Long-Term Vision Damage in 31-year Old Male
Abnormally high doses of sildenafil citrate could lead to long-term – and perhaps permanent – vision damage, suggests a recent case report in Retinal Cases & Brief Reports. Sildenafil citrate is the active ingredient in Viagra, a phosphodiesterase type 5 (PDE5) inhibitor used to treat erectile dysfunction (ED). It is sometimes used to treat pulmonary […]
Half of Women Say Ejaculation Is Important
Many women consider a man’s ejaculation, including its volume and intensity, to be important, although their views vary widely, according to new research in the Journal of Sexual Medicine. Past research has shown that premature ejaculation can affect both men and their female partners. But little was known about the ways other aspects of ejaculation, […]